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Ha KN, Chen Y, Cai J, Sternberg P Jr
Individuals with severe osteoarthritis, inflammatory arthropathies like rheumatoid arthritis, or significant muscle loss may benefit from a multidisciplinary approach combining GLP-1 therapy with physical therapy and rheumatology input
Are they good long term
Technically, when the FDA first yanked tirzepatide off its shortage list in October 2024, both 503As and 503Bs could no longer legally make copycats (with one notable exception for the smaller 503As, who could still fill individual prescriptions if there was a medical reason the patient needed a slightly different version than the brand-name drugmore on this later)
Clinical observations from practitioners are positive
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